“We’re all walking around with some mild cognitive impairment,” said Mike Yassa, a neuroscientist at UC Irvine. “Based on everything we know about the brain, two of the things that are really good for it are physical activity and novelty. A thing that’s very bad for it is chronic and perpetual stress.” Living through a pandemic—even for those who are doing so in relative comfort—“is exposing people to microdoses of unpredictable stress all the time,” said Franklin, whose research has shown that stress changes the brain regions that control executive function, learning, and memory.

Late-Stage Pandemic Is Messing With Your Brain